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PANDAS: A Guide for Parents

PANDAS stands for pediatric autoimmune neuropsychiatric disorders associated with streptococcus. The syndrome involves sudden and often major changes in personality, behavior, and movement in children following an infection involving Streptococcus pyogenes (streptococcal-A infection).

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What are the symptoms?

The symptoms of PANDAS start suddenly, about four to six weeks after a strep infection. They include behaviors similar to obsessive-compulsive disorder (OCD) and Tourette syndrome. These symptoms can interfere with schooling and quickly become debilitating. Symptoms worsen and reach their peak usually within two to three days, unlike other childhood psychiatric illnesses that develop more gradually.

Psychological symptoms may include:

obsessive, compulsive, and repetitive behaviors

separation anxiety, fear, and panic attacks

incessant screaming, irritability, and frequent mood changes

emotional and developmental regression

visual or auditory hallucinations

depression and suicidal thoughts

Physical symptoms may include:  

tics and unusual movements

sensitivities to light, sound, and touch

deterioration of small motor skills or poor handwriting

hyperactivity or an inability to focus

memory problems

trouble sleeping

refusing to eat, which can lead to weight loss

joint pain

frequent urination and bedwetting

near catatonic state

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